A new study in Cell Reports on intermittent fasting was just published. It may be a game changer when it comes to intermittent fasting. Here is the summary of the article, provided by Cell Reports:
"Caloric restriction (CR) has been shown to prevent the onset of insulin resistance and to delay age-related physiological decline in mammalian organisms. SIRT1, a NAD+-dependent deacetylase enzyme, has been suggested to mediate the adaptive responses to CR, leading to the speculation that SIRT1 activation could be therapeutically used as a CR-mimetic strategy. Here, we used a mouse model of moderate SIRT1 overexpression to test whether SIRT1 gain of function could mimic or boost the metabolic benefits induced by every-other-day feeding (EODF). Our results indicate that SIRT1 transgenesis does not affect the ability of EODF to decrease adiposity and improve insulin sensitivity. Transcriptomic analyses revealed that SIRT1 transgenesis and EODF promote very distinct adaptations in individual tissues, some of which can be even be metabolically opposite, as in brown adipose tissue. Therefore, whereas SIRT1 overexpression and CR both improve glucose metabolism and insulin sensitivity, the etiologies of these benefits are largely different."
You read the entire study here: http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30081-X
Sites We Love
The Baker Chick
The Candida Diet
Super Healthy Kids
Wake Up World
No Meat Athlete
American Nutrition Assoc.
Lean it Up
Muscle and Fitness
“Physical fitness is not only one of the most important keys to a healthy body, it is the basis of dynamic and creative intellectual activity.”
The site does not provide medical or legal advice. This website is for information purposes only. Viewing this website, receipt of information contained on this website, or the transmission of information from or to this website does not constitute a physician-patient relationship. The medical and/or nutritional information on this site is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay seeking it because of something you have read on this website. Use of this website constitutes acknowledgement and acceptance of these limitations and disclaimers.